Culturelle® IBS Complete Support

Clinically shown to relieve abdominal pain, bloating, constipation and diarrhea due to IBS

Culturelle® IBS Complete Support is clinically shown to help relieve the intensity & reduce the frequency of severe digestive symptoms associated with all types of IBS. Imagine life with more symptom free days!

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The Microbiome & Managing IBS

There is no cure for IBS, but there are things you can do to ease the severity and duration of your symptoms. When you have an imbalance in your gut’s microbiome, it can trigger IBS symptoms such as bloating, abdominal pain, gas, constipation and/or diarrhea. Culturelle® IBS Complete Support is a medical food that goes beyond symptom relief to help at the source of your issues by using HMO bioactive prebiotics to selectively feed good bacteria. Restoring the balance of bacteria in the gut microbiome may help by strengthening the gut barrier which may improve the health of your gut and balance your immune system.

Benefits of Culturelle® IBS Complete Support Packets

  • Clinically shown to relieve abdominal pain, bloating, constipation and diarrhea due to IBS
  • More symptom free days
  • Convenient one-a-day dose in easy to use, flavorless packets

HMO Bioactive Prebiotics: Clinically Shown to Make Real Changes

HMOs (human milk oligosaccharides) are unique prebiotics naturally found in breastmilk that help fortify and build a healthy gut. By replicating two of those nutrients in Culturelle® IBS Complete Support, our ingredients work naturally with your body to make real changes to target the source of your digestive issues (the HMOs in our product are not from human milk). In a clinical study with more than 300 participants, people using Culturelle® IBS Complete Support every day reported improvements in their symptoms:

  • 58% reduction of days with abdominal pain
  • Decreased bloating by 59%
  • More normal bowel movements

Find Relief with A Medical Food

Culturelle® IBS Complete Support is a medical food to be used only under medical supervision and direction. Medical foods are specifically formulated for the dietary management of a disease or condition that has distinctive nutritional requirements that cannot be met by typical diet alone. Culturelle® IBS Complete Support helps you nutritionally manage your symptoms, such as bloating, constipation, diarrhea, and abdominal pain. Your healthcare provider may choose to recommend Culturelle® IBS Complete Support along with prescribing medication or other products.

Taking a Daily Prebiotic & What to Expect

Culturelle® IBS Complete Support has a proprietary formulation of prebiotics and is a medical food for dietary management of irritable bowel syndrome (IBS). The recommended dose for adults and children 12 years of age and older is one packet once daily, mixed in liquids or food. Dosage can be altered as directed by a healthcare provider.

Since Culturelle® IBS Complete Support makes real changes in your gut microbiome, it’s not unusual to experience some mild discomfort initially, such as gas and bloating. This is normal and a good sign. Your microbiome is starting to work the way it should to restore balance and help relieve IBS symptoms. Shown in a clinical study to improve IBS symptoms within 4 weeks.

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Products You Can Trust

When you choose Culturelle®, you choose the highest standards of purity and potency. Culturelle® guarantees the contents in each packet matches that used in the open label clinical study.

Each serving of Culturelle® IBS Complete Support is individually sealed to prevent moisture, light, heat and air from getting in. This cutting-edge protective packaging also means you don’t need to store Culturelle® IBS Complete Support in the refrigerator. All you need to do is keep the box in a cool, dry place away from direct sunlight.

Our Promise to YOU

We’re on a mission to inspire better health and wellness for you and your family.

We believe in integrity, so we hold ourselves to the highest standards of truth.

We believe in the natural power of your body’s microbiome and in scientific research and products that will unlock its full potential.

We believe in uncompromising quality, safety and proven efficacy.

We believe in empowering you to embrace every day with confidence.

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Shown in an open label clinical study including 317 IBS participants.

Ratings & Reviews

This area allows consumers like you to express their own opinions and comments. Culturelle does not represent or warrant the accuracy of any statements or product claims made here, nor endorses any opinions expressed within this section.


What are HMOs?

Human milk oligosaccharides (HMOs) are a type of complex carbohydrate found in breast milk. They’re known as natural digestive nutrients because of their prebiotic properties. Prebiotics work with your body to help support the balance of good bacteria your body needs.

What do HMOs do?

Simply put, HMOs work by selectively nourishing and stimulating the growth of your own good gut bacteria, activating them to thrive and outperform bad bacteria. Their benefits in breast milk have long been known to help build and fortify healthy guts in infants, and studies show they can benefit adult gut health as well by targeting the source of gut issues and making real changes to your digestive system.

Are your HMOs made from human milk?

No. We mirrored these natural digestive nutrients to create our own unique and targeted nutrient formulation. Culturelle IBS Complete Support doesn’t contain human milk, but just like nature’s own HMOs, our ingredients can help restore balance in your gut microbiome, ultimately helping relieve your digestive symptoms.

How are HMOs different from a probiotic?

Probiotics used for the digestive system work by introducing good bacteria into your body to rebalance your own microbiome. HMOs are unique targeted prebiotics in that they nourish only select gut bacteria so that your microbiota produces the nutrients your body needs to help restore balance in your gut. In other words, HMOs work naturally with your body to make real changes to your microbiota.

Who can/should take Culturelle IBS Complete Support?

Culturelle IBS Complete Support is a medical food and should be taken under the supervision of a doctor. It is formulated to help relieve the severity and frequency of IBS symptoms in adults (12 and older). Culturelle® IBS Complete Support may be used by all IBS subtypes including IBS-M, IBS-C and IBS-D patients.

Can Culturelle IBS Complete Support be taken by those who are lactose intolerant?

It may contain traces of lactose (milk), however the amount of lactose contained is very small and ordinarily too low to trigger any symptoms of lactose intolerance. Lactose intolerant participants in a clinical trial reported no adverse events.

What about other food sensitivities and allergies?

We're sensitive to food sensitivities and allergies, which is why we created Culturelle IBS Complete Support to be free from: artificial flavors, sweeteners, and coloring; yeast; preservatives; gluten; GMOs; soy, peanuts, tree nuts, wheat, eggs, fish, and shellfish.

Can Culturelle IBS Complete Support be taken when on FODMAP?

Yes, Culturelle IBS Complete Support is FODMAP-friendly! Not all oligosaccharides are covered by the "O" in FODMAP. The FODMAP oligosaccharides generally contain the sugar, fructose, and are found in vegetables, fruits, legumes, etc. These FODMAP oligosaccharides are digested by a large number of intestinal bacteria, many of which produce gases that generate symptoms such as bloating. The human milk oligosaccharides in Culturelle IBS Complete Support do not contain fructose. Also, because of their unique structure, only a very small number of specific intestinal bacteria can digest them, and these specific bacteria are not known gas producers.

Are there any side effects?

Since Culturelle IBS Complete Support makes real changes in your gut microbiome, it is not unusual to experience some mild side effects when you start taking it. Research shows that over 96% of people who participated in our clinical study found the HMOs contained in Culturelle IBS Complete Support to be tolerable. The most common temporary side effects were mild gastrointestinal (GI) symptoms such as abdominal pain, gas, and bloating. These are perfectly normal and actually an indication that your microbiome is beginning to improve. These sensations tend to disappear without any intervention after a few days, though for some people it may take slightly longer for their system to settle. While it might feel a little unpleasant during these first days, know that these are signs that your microbiome is changing to help you reclaim control of your digestive health, so it’s worth sticking with it. If you are still experiencing these symptoms after the first few weeks but they are manageable, it is perfectly safe to continue with the products. Your gut will find a new balance by itself within the first month or two. If, however, you experience any more serious side effects, such as nausea or increased IBS symptoms, you should stop taking the product and seek advice from your doctor.

How long does it take to have results?

In our clinical study, patients reported significant benefits in 4 weeks. Participants have told us that they start seeing changes after 1-2 weeks. Everyone is different, so it may take your gut microbiome a little longer to rebalance. Developed for daily and proactive dietary management of IBS, continued daily use is suggested to help sustain nutritional support.

What clinical evidence does Culturelle have for the benefits of Culturelle IBS Complete Support?

In an open label clinical study of over 300 participants, patients using Culturelle® IBS Complete Support everyday reported significant improvement in their symptoms:

  • Fewer days with stomach pain
  • More normal bowel movements
  • Reduced bloating severity
  • Quality of life improvements as reported by users – such as energy, mood, and irritability

Directions for Use

Directions For Use

Box contains: 28 easy to mix packets 

Daily dose: 1 packet

Ingredients: Proprietary formulation (2’-Fucosyllactose, Lacto-N-neotetraose).

Mix with foods & drinks, hot or cold. Dissolve contents of 1 packet in water or other beverage or sprinkle on top of any food. Take one (1) stick pack per day and consume immediately after opening the packet. Culturelle® IBS Complete Support is an odorless powder with neutral taste. It imparts no taste in any flavored food or drink. In water, may have a slight (mild) sweetness. Please use under medical supervision.

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